Description
In humans and other mammals, the suprachiasmatic nuclei (SCN) of the hypothalamus controls a “master clock” that aligns the internal circadian clock to a 24-hour light–dark cycle. This cycle controls the production of melatonin, a hormone that promotes sleep in healthy individuals. A healthy individual is generally entrained to a sleep-wake cycle which repeats around every 24.2 hours but can vary between 23.8 to 27.1 hours. Although Melatonin is only one of many changes throughout an individual’s 24-hr circadian cycle, it is readily measured in saliva. In a healthy 24-hour circadian cycle, Melatonin production drops significantly after awakening and stays low during daylight hours, while gradually rising after sunset when the body increases sleep propensity (typically about 2 hours before a person’s natural sleep onset or bedtime).
Why Saliva-Based Sleep Assessment from Salimetrics?
- Convenient, All-Inclusive, and Easy to Use Sampling Kit with Cold Chain Managed, Round-Trip Shipping
- Most Reliable, Biologically Accurate, Evidence-Based Assessment of Circadian Rhythm Available
- Supported by Researchers and Clinicians
- 9 Sample Sleep Study Screens for Most Sleep-Related Disorders
- Performance Validated
- Safe for All Ages, Including Children and Elderly
- Flexible, At-Home, or In-Sleep Center Collection Protocol




